pap smear

Pap smear for women

A Pap smear, also called a Pap test, is a procedure to test for cervical cancer in women. A Pap smear involves collecting cells from your cervix — the lower, narrow end of your uterus that’s at the top of your vagina.
Detecting cervical cancer early with a Pap smear gives you a greater chance at a cure. A Pap smear can also detect changes in your cervical cells that suggest cancer may develop in the future.

Why it’s done

A Pap smear is used to screen for cervical cancer. The Pap smear is usually done in conjunction with a pelvic exam. In women older than age 30, the Pap smear may be combined with a test for human papillomavirus (HPV) — a common sexually transmitted infection that can cause cervical cancer in some women.

Who should have a Pap smear?

You and your doctor can decide when it’s time for you to begin Pap smear testing and how often you should have the test. In general, doctors recommend beginning Pap smear testing at age 21 and then every two or three years. After age 30, Pap smears are generally recommended every three years, or every five years when the Pap smear is combined with an HPV test.
If you have certain risk factors, your doctor may recommend more-frequent Pap smears, regardless of your age. These risk factors include:

  • A diagnosis of cervical cancer or a Pap smear that showed precancerous cells
  • Exposure to diethylstilbestrol (DES) before birth
  • HIV infection
  • Weakened immune system due to organ transplant, chemotherapy or chronic corticosteroid use

Who can consider stopping Pap smears?

Discuss your screening options with your doctor. In certain situations a woman and her doctor may decide to end Pap testing, such as:

  • After total hysterectomy.
  • After a total hysterectomy — surgical removal of the uterus including the cervix — ask your doctor if you need to continue having Pap smears. If your hysterectomy was performed for a noncancerous condition, such as uterine fibroids, you may be able to discontinue routine Pap smears. But if your hysterectomy was for a precancerous or cancerous condition of the cervix, your doctor may recommend continuing routine Pap smears.

  • Older age
  • Groups agree that older women may consider stopping routine Pap tests. ACS guidelines suggest a woman older than age 65 can stop having tests if she’s had regular screenings with normal results. USPSTF guidelines recommend against Pap testing for women older than age 65 who have had routine Pap testing in the past and are not at high risk of cervical cancer. ICSI guidelines recommend women ages 65 to 70 may consider stopping Pap testing if their last three tests have been negative and they’ve had no abnormal tests in 10 years. ACOG guidelines say that women older than age 65 can stop Pap tests if they’ve had three consecutive negative Pap tests in the last 10 years, or two consecutive negative Pap tests combined with negative HPV tests in the last 10 years, with the most recent test performed within the past 5 years. Discuss your options with your doctor and together you can decide what’s best for you based on your risk factors. If you are sexually active with multiple partners, your doctor may recommend continuing Pap smear testing.

False-negative results

A false-negative result doesn’t mean that a mistake was made. Factors that can cause a false-negative result include:

  • An inadequate collection of cells
  • A small number of abnormal cells
  • Blood or inflammatory cells obscuring the abnormal cells

Although it’s possible for abnormal cells to go undetected, time is on your side. Cervical cancer takes several years to develop. And if one test doesn’t detect the abnormal cells, the next test most likely will.


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Dr. Saffarzadeh


Dr. Saffarzadeh specializes Gynecological Laparoscopic Infertility fellowship at the University of Medical Sciences and two from France.


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